جهت دسترسی به کاربرگه ی زیر، از این لینک استفاده کنید. http://78.39.227.9/handle/Hannan/45156
Title: A genome-wide association study of marginal zone lymphoma shows association to the HLA region
Authors: Vijai, Joseph;Wang, Zhaoming;Berndt, Sonja I.;Skibola, Christine F.;Slager, Susan L.;de Sanjose, Silvia;Melbye, Mads;Glimelius, Bengt;Bracci, Paige M.;Conde, Lucia;Birmann, Brenda M.;Wang, Sophia S.;Brooks-Wilson, Angela R.;Lan, Qing;de Bakker, Paul I. W.;Vermeulen, Roel C. H.;Portlock, Carol;Ansell, Stephen M.;Link, Brian K.;Riby, Jacques;North, Kari E.;Gu, Jian;Hjalgrim, Henrik;Cozen, Wendy;Becker, Nikolaus;Teras, Lauren R.;Spinelli, John J.;Turner, Jenny;Zhang, Yawei;Purdue, Mark P.;Giles, Graham G.;Kelly, Rachel S.;Zeleniuch-Jacquotte, Anne;Ennas, Maria Grazia;Monnereau, Alain;Bertrand, Kimberly A.;Albanes, Demetrius;Lightfoot, Tracy;Yeager, Meredith;Chung, Charles C.;Burdett, Laurie;Hutchinson, Amy;Lawrence, Charles;Montalvan, Rebecca;Liang, Liming;Huang, Jinyan;Ma, Baoshan;Villano, Danylo J.;Maria, Ann;Corines, Marina;Thomas, Tinu;Novak, Anne J.;Dogan, Ahmet;Liebow, Mark;Thompson, Carrie A.;Witzig, Thomas E.;Habermann, Thomas M.;Weiner, George J.;Smith, Martyn T.;Holly, Elizabeth A.;Jackson, Rebecca D.;Tinker, Lesley F.;Ye, Yuanqing;Adami, Hans-Olov;Smedby, Karin E.;De Roos, Anneclaire J.;Hartge, Patricia;Morton, Lindsay M.;Severson, Richard K.;Benavente, Yolanda;Boffetta, Paolo;Brennan, Paul;Foretova, Lenka;Maynadie, Marc;McKay, James;Staines, Anthony;Diver, W. Ryan;Vajdic, Claire M.;Armstrong, Bruce K.;Kricker, Anne;Zheng, Tongzhang;Holford, Theodore R.;Severi, Gianluca;Vineis, Paolo;Ferri, Giovanni M.;Ricco, Rosalia;Miligi, Lucia;Clavel, Jacqueline;Giovannucci, Edward;Kraft, Peter;Virtamo, Jarmo;Smith, Alex;Kane, Eleanor;Roman, Eve;Chiu, Brian C. H.;Fraumeni, Joseph F.;Wu, Xifeng;Cerhan, James R.;Offit, Kenneth;Chanock, Stephen J.;Rothman, Nathaniel;Nieters, Alexandra
Issue Date: 2015
Publisher: Nature Pub. Group
Description: Marginal zone lymphoma (MZL) is the third most common subtype of B-cell non-Hodgkin lymphoma. Here we perform a two-stage GWAS of 1,281 MZL cases and 7,127 controls of European ancestry and identify two independent loci near BTNL2 (rs9461741, P=3.95 × 10−15) and HLA-B (rs2922994, P=2.43 × 10−9) in the HLA region significantly associated with MZL risk. This is the first evidence that genetic variation in the major histocompatibility complex influences MZL susceptibility.
URI: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4287989/pdf/
http://nrs.harvard.edu/urn-3:HUL.InstRepos:14065347
Other Identifiers: Vijai, J., Z. Wang, S. I. Berndt, C. F. Skibola, S. L. Slager, S. de Sanjose, M. Melbye, et al. 2015. “A genome-wide association study of marginal zone lymphoma shows association to the HLA region.” Nature Communications 6 (1): 5751. doi:10.1038/ncomms6751. http://dx.doi.org/10.1038/ncomms6751.
2041-1723
Appears in Collections:HSPH Scholarly Articles

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