جهت دسترسی به کاربرگه ی زیر، از این لینک استفاده کنید. http://78.39.227.9/handle/Hannan/18196
Title: Baylis-Hillman reaction assisted parallel synthesis of 3, 5-disubstituted isoxazoles and their in vivo bioevaluation as antithrombotic agents
Authors: Batra, Sanjay;Roy, Amrendra K;Patra, A;Bhaduri, A P;Surin, W R;Raghavan, S A V;Sharma, P;Kapoor, Kapil;Dikshit, Madhu
Keywords: Baylis-Hillman reaction;Isoxazolecarbaldehyde;isoxazole;nucleophilic substitution;substituted piperazine;antithrombotic activity;platelet aggregation
Issue Date: 2004
Description: The solution phase parallel synthesis involving reactions of Baylis-Hillman products of 3-substituted-5-isoxazolecarbaldehydes with nucleophiles and their in vivo antithrombotic evaluations are described along with the results of in vitro platelet aggregation inhibition assay of a few compounds. Results of the detailed evaluation of one of the compounds as an inhibitor of platelet aggregation are also presented.
URI: Bioorg. Med. Chem., 12(9), 2059-2077
http://hdl.handle.net/123456789/34
Appears in Collections:Medicinal and Process Chemistry

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